The Reds secured a dramatic win in the Merseyside derby on Sunday before coming from behind to beat Burnley on Wednesday and will be licking their lips at the prospect of beating the Cherries, who have lost four of their last five matches.
However, Bournemouth’s last game saw them triumph against Huddersfield so they will have an extra spring in their step.
They also have the incentive of leapfrogging Everton into sixth place if they can anything out of the game.
Meanwhile, Jurgen Klopp’s men – who will go top of the Premier League for a few hours at least with a win – may have one eye on their crucial Champions League match at home to Napoli on Tuesday night.
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What the managers are saying
Eddie Howe (Bournemouth): “We are going to have to be absolutely excellent in every department. It is a big challenge for us.
“We know their strengths, how good they can be. For us we are looking at a top performance and hopefully the result will come our way.”
Jurgen Klopp (Liverpool): “Bournemouth are in a good moment. It was always really hard work for the opponent.
“They are full of confidence. To be first in the table would be nice but it would probably only last a few hours.”
Bournemouth will be without Lewis Cook for the rest of the season because of a serious knee injury, while Dan Gosling misses the Liverpool game with his own knee problem.
Defender Adam Smith (knee) continues his rehabilitation.
Klopp has a growing number of injuries to contend with as Sadio Mane (foot), Dejan Lovren (concussion) and Nathaniel Clyne (muscle) are all confirmed absentees for Saturday’s game.
Defender Joe Gomez is out for around six weeks with a fractured leg, while Dominic Solanke (groin) is also out as are long-term casualties Alex Oxlade-Chamberlain and Rhian Brewster (both knee)
Bournemouth: Begovic; Francis, S Cook, Ake, Daniels; Brooks, Surman, Lerma, Fraser; King, Wilson
Liverpool: Alisson; Alexander-Arnold, Matip, Van Dijk, Robertson; Fabinho, Milner, Keita; Salah, Shaqiri, Origi